Article by lab colleague Cees van der Poel entitled “Follicular Dendritic Cells Modulate Germinal Center B Cell Diversity through FcgRIIB” is published in Cell reports (open access).
Highlights:
• Stromal FcγRIIB deficiency causes increased germinal center diversity
• Absence of FcγRIIB on Follicular Dendritic Cells (FDCs) supports persistence of low Somatic HyperMutation (SHM) B cell clones
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