Poster / Abstract
(32) C. Castrillon, L. Simoni*, T. van den Broek*, C. van der Poel*, M.C. Carroll. Naive cells in an autoimmune environment: a single cell level exploration (79). Program in Cellular and Molecular Medicine Retreat, North Falmouth, MA, USA. Sept. 2019.
(31) T. van den Broek, C. Castrillon, E. Akama-Garren, K. Holscher, J. O’flynn, C. van der Poel, M.C. Carroll. The evolution of WT B-cells in the autoreactive germinal center (81). Program in Cellular and Molecular Medicine Retreat, North Falmouth, MA, USA. Sept. 2019.
(30) T. van den Broek, C. van der Poel, J. O’flynn, E. Akama-Garren, K. Holscher, M.C. Carroll. Autoreactivity supports the maintenance and active participation of wild-type B cells in the germinal center (W.67). FOCIS, Boston, June 2019.
(29) Michael C. Carroll, Gabriel D. Victora, Søren E. Degn, T. van den Broek, C. van der Poel. Evolution of Self-reactive Germinal Centers and Epitope Spreading. Keystone Symposia B cell – T cell interaction (J6), Keystone, Colorado. Febr. 2019.
(28) T. van den Broek, C. van der Poel, J. O’flynn, E. Akama-Garren, K. Holscher, M.C. Carroll. Autoreactivity supports the maintenance and active participation of wild-type B cells in the germinal center. Keystone Symposia B cell – T cell interaction (J6), Keystone, Colorado (poster number 3028) Febr. 2019.
(27) S. Albani, JY Leong, T. van den Broek. Immune Therapy of Rheumatoid Arthritis Patients with a Microbiome-Derived, Self/Non-Self Peptide Induces Clinically Relevant Immune Tolerance Pivoting on Immune Checkpoint-Expressing, Therapy-Induced Tregs [abstract]. Arthritis Rheumatol. 2018; 70 (suppl 10). 2018 ACR/ARHP Annual Meeting, Chicago, Illinois (abstract number 2052)
(26) T. van den Broek, J. O’flynn, E. Akama-Garren, K. Holscher, C.E. van der Poel, M.C. Carroll. Wild-type B cell involvement in the autoreactive germinal center. Program in Cellular and Molecular Medicine Retreat, North Falmouth, MA, USA 2018.
(25) J.H.S. Chan, T. van den Broek, J.Y. Leong, M. Rossetti, R. Spreafico, S. Albani. Reactivation of Immune Checkpoints by an Epitope-Specific Vaccine Reinstates Tolerogenic Pathways and Induces Clinical Amelioration in Patients with Rheumatoid Arthritis. Ann Rheum Dis 2018; Vol 77 (Suppl 2): SAT0232. EULAR Scientific meeting 2018, Amsterdam, the Netherlands (10.1136/annrheumdis-2018-eular.6126)
(24) J.H.S. Chan, T. van den Broek, J.Y. Leong, M. Rossetti, R. Spreafico, S. Albani. Induction of Immune Tolerance through an Epitope-Specific Vaccine Induces Clinical Amelioration in Patients with Rheumatoid Arthritis. Arthritis Rheumatol. 2017; Suppl 10: 1462. ACR/AHRP Scientific meeting 2017, San Diego, CA., USA
(23) J.Y. Leong, R. Ong Jr., J. Li, T. van den Broek, R. Spreafico, M. Rossetti, S. Albani. Deciphering the Immunome of Clinically Effective Immune Tolerization in Rheumatoid Arthritis. Arthritis Rheumatol. 2015; Suppl 10: 67.
(22) T. van den Broek, H. Shamay, H.G. Otten, A.W.L. Schadenberg, I.R. Cohen, B. Prakken, N.J.G. Jansen, F. van Wijk. T- and B-cell dynamics after neonatal thymectomy. Bertine Koperberg Conference 2014, Soesterberg, The Netherlands
(21) T. van den Broek*, E.M.D. Delemarre*, J. Meerding, E. Wehrens, F. Broere, N. Wulffraat, M. Boes, B. Prakken# and F. van Wijk# (*,# equally contributed) Autologous stem cell transplantation in autoimmune arthritis restores immune homeostasis by renewal of the natural Treg compartment. Dutch Society for Immunology Annual Meeting, December 2013: P108, Noordwijkerhout, the Netherlands
(20) R. Spreafico, M. Rossetti, T. van den Broek, O. Morrow, S. Albani. Epigenetic Features as Predictive Markers of Responsiveness to Epitope-Specific Therapy in Rheumatoid Arthritis. Arthritis Rheum 2012;64 Suppl 10 :427, ACR/AHRP Scientific meeting 2012, Washington, D.C., USA
(19) T. van den Broek*, E. Delemarre*, J. Meerding, E. Wehrens, F. Broere, N. Wulffraat, M. Boes, B. Prakken# and F. van Wijk# (*,# equally contributed) Autologous stem cell transplantation in autoimmune arthritis restores immune homeostasis by renewal of the natural Treg compartment. Dutch Society for Immunology Annual Meeting, December 2011: P51, Noordwijkerhout, the Netherlands
(18) T. van den Broek*, E. Delemarre*, J. Meerding, E. Wehrens, F. Broere, N. Wulffraat, M. Boes, B. Prakken# and F. van Wijk# (*,# equally contributed) Autologous stem cell transplantation in autoimmune arthritis restores immune homeostasis by renewal of the natural Treg compartment Pediatric Rheumatology 2011, 9(Suppl 1):P183 PReS Scientific meeting 2011, Bruges, Belgium.
(17) E. Delemarre, T. van den Broek, J. Meerding, E. Wehrens, N. Wulffraat, B. Prakken, F. van Wijk. Autologous Stem Cell Transplantation in Autoimmune Arthritis Restores Immune Homeostasis by Renewal of the Natural Treg Compartment. Clinical Immunology, Abstract Supplement S47. FOCIS 2011, Washington D.C. USA
(16) T. van den Broek, N. Schechter, C. Cover, N. Seaver and S. Albani. Clinical Control Induced by Epitope Specific Therapy in Rheumatoid Arthritis Is Associated with T-Cell Immune Deviation from Pro-Inflammatory (Th1/Th17) to Regulatory Phenotype (Th2/Treg). Arthritis Rheum 2009;60 Suppl 10 :434 ACR/AHRP Scientific meeting 2009, Philadelphia, USA
(15) T. van den Broek, N. Schechter, C. Cover, N. Seaver, F. Bughio, N. Shen and S. Albani, Immunological Mechanisms Related to Clinical Responsiveness Differ Between Methotrexate Monotherapy and Methotrexate and Etanercept Co-Treatment in Rheumatoid Arthritis. Arthritis Rheum 2009;60 Suppl 10 :1023 ACR/AHRP Scientific meeting 2009, Philadelphia, USA
(14) T. van den Broek, N. Schechter, C. Cover, N. Seaver, F. Bughio, N. Shen, S. Albani. Clinical Control in Patients with Rheumatoid Arthritis Is Associated with Restoration of Diverse Subpopulations of Regulatory T Cells, including a Novel Subtype Relying on the PD1-B7-H1 Pathway. Arthritis Rheum 2009;60 Suppl 10 :435 ACR/AHRP Scientific meeting 2009, Philadelphia, USA
(13) T. van den Broek, N. Schechter, N. Seaver, A. Nichols, C. Cover, S. Albani. Clinical Control Induced by Epitope-specific Therapy in Rheumatoid Arthritis is Associated with T Cell Immune Deviation from Pro-inflammatory (Th1/Th17) to Regulatory Phenotype (Th2/Treg). AHSC Frontiers Biomedical Research, Tucson, Arizona, Poster, 10/2009. USA
(12) J. Vastert, W. de Jager, T. van den Broek, F. Verweij, M. R. Klein, W. Kuis, F. Van Wijk, S. Albani, B. J. Prakken. Anti-TNFalpha Therapy in Juvenile Idiopathic Arthritis is Associated with Changes in Effector T-cell Populations. Ann Rheum Dis 2009;68(Suppl3):541
(11) T. van den Broek, N. Schechter, N. Seaver, A. Nichols, C. Cover, S. Albani. Clinical Remission Induced by Epitope-specific Therapy in Rheumatoid Arthritis is Associated with T Cell Immune Deviation from Pro-inflammatory (Th1/Th17) to Regulatory Phenotype (Th2/Treg). Clinical Immunology 2009; Vol 131 (Supplement): S69, T.66. FOCIS 2009, San Francisco, USA
(10) T. van den Broek, N. Schechter, N. Seaver, A. Nichols, C. Cover, S. Albani. Clinical Remission Induced by Epitope-specific Therapy in Rheumatoid Arthritis is Associated with T Cell Immune Deviation from Pro-inflammatory (Th1/Th17) to Regulatory Phenotype (Th2/Treg). Fourth Frontiers in Immunobiology and Immunopathogenesis Symposium, Tucson, Arizona, Poster, 03/2009.USA
(9) T. van den Broek, N. Schechter, N. Seaver, A. Nichols, C. Cover, S. Albani. Clinical Remission Induced by Epitope-specific Therapy in Rheumatoid Arthritis is Associated with T Cell Immune Deviation from Pro-inflammatory (Th1/Th17) to Regulatory Phenotype (Th2/Treg). 2009 Midwinter Conference of Immunologists (Cumulative Poster Abstracts) Page 73, at Asilomar, USA
(8) T. van den Broek; E. Keogh; F. van Wijk; N. Ghahramani; A. van de Ven; S. Albani. Susceptibility to Epitope Specific Immunotherapy of Rheumatoid Arthritis Relies on the Expression of Co-Stimulatory Molecules Associated with T Cell Anergy and Tolerance. Arthritis & Rheumatism Sept 2008; Vol. 58, No. 9 (Abstract Supplement): S845, 1848.
(7) T. van den Broek; E. Keogh; F. van Wijk; N. Ghahramani; A. van de Ven; S. Albani. Susceptibility to Epitope Specific Immunotherapy of Rheumatoid Arthritis Relies on the Expression of Co-Stimulatory Molecules Associated with T Cell Anergy and Tolerance. Clinical Immunology 2008; Vol. 127 (Abstract Supplement): p586, Sa.20.
(6) W. Hellings; F.L. Moll; B. Verhoeven; D.P. de Kleijn; J.P.P. de Vries; K.A. Seldenrijk; T. van den Broek; E. Busser; E. Velema; G. Pasterkamp. Gender Associated Differences in Plaque Phenotype of Patients Undergoing Carotid Endarterectomy. Eur Heart J 2006; Vol.27 (abstract Supplement):4650
(5) W. Hellings; F.L. Moll; B. Verhoeven; D.P. de Kleijn; J.P.P. de Vries; K.A. Seldenrijk; T. van den Broek; E. Busser; E. Velema; G. Pasterkamp. Gender Associated Differences in Plaque Phenotype of Patients with Hemodynamically Significant Carotid Stenosis. Circulation, 114 (18):411-411 Suppl. S OCT 31 2006
(4) A. Rodriguez-Feo, G. Pasterkamp, C.E. van der Poel, B. van Middelaar, T. van den Broek, D.P.V. de Kleijn. Cavtratin Reduces Matrix-metalloproteinase-2 Levels and Flow-induced Outward Arterial Remodeling. American Heart Journal 2005; Vol.112 (Abstract Supplement):260
(3) A. Rodriguez-Feo, G. Pasterkamp, C.E. van der Poel, B. van Middelaar, T. van den Broek, D.P.V. de Kleijn. Cavtratin Reduces Matrix-metalloproteinase-2 Levels and Flow-induced Outward Arterial Remodeling. European Heart Journal 2005; Vol.26 (Abstract Supplement):580
(2) G. Pasterkamp; E. Velema; A. Schoneveld; B. Verhoeven; P. de Bruin; K.A. Seldenrijk; T. van den Broek; D.P. de Kleijn; F.L. Moll. Statin Treatment and the Paradoxil Effect on Plaque Phenotype: A Study in Advanced Human Atherosclerotic Plaques. Atherosclerosis supplement, 5 (1):15-15 APR 2004
(1) T. van den Broek, E. Velema, A.H. Schoneveld, E. Busser, J.P. de Vries, D.P.V. de Kleijn, F.L. Moll, G. Pasterkamp. Risk Factors for Atherosclerosis and Carotid Plaque Phenotype. European Heart Journal vol.25 Abstract Supplement August/September 2004 P623 page102