T:B cell interactions in lymphoid structures
– aiming to drive meaningful clinical advancements –
Center for Translational Immunology, UMC Utrecht
Utrecht, the Netherlands
T:B cell lab
We investigate human T and B cell biology to uncover disease mechanisms and support clinical translation.
Our team studies how T and B cells interact in human lymphoid structures, with a particular focus on the developing pediatric immune system and chronic inflammation. By exploring these contexts, we aim to better understand how adaptive immune interactions are regulated in human tissues and how they contribute to disease progression and resolution.
About the lab
The lab is part of the Center for Translational Immunology (CTI), which brings together leading immunology expertise to conduct all immunological disease research at University Medical Center Utrecht.
Located in the Wilhelmina Children’s Hospital next to UMC Utrecht and the Princess Maxima Center, the lab benefits from access to diverse clinical samples, enhancing translational research opportunities across diseases and enabling close collaboration with clinicians to improve diagnostics and patient outcomes.
News
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Successful MSCA-DN Consortium Meeting in Utrecht
Over the past three days, many partners of our TISSUE consortium travelled to Utrecht to meet face-to-face and work together on an ambitious goal: shaping the future training of early-career scientists in tissue immunology. It was a great opportunity to bring together colleagues from several of our partner institutions and to strengthen the connections within…
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Emma Schrage finalizes bachelor thesis
Emma has submitted an incredibly interesting thesis entitled CD4+ T Cell Development During Early Life: Towards Age-Adapted Vaccination. A highly relevant topic, as our immune system changes profoundly during early life, with important consequences for how we respond to infections and vaccines. Emma’s work addresses how CD4+ T cells develop and mature during this critical…
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Lymph Node Research UK Satellite Symposium with EFIS Study Group
I am very happy to announce that the EFIS Study Group: Lymphoid Structures: Orchestrators of Immunity is invited to join the Lymph Node Research UK for a Satellite Symposium at the BSI in Glasgow (nov 30th 2026)Hope to see many of you there to discuss exciting lymph node related science!
