T:B cell interactions in lymphoid structures
– aiming to drive meaningful clinical advancements –
Center for Translational Immunology, UMC Utrecht
Utrecht, the Netherlands
T:B cell lab
We investigate human T and B cell biology to uncover disease mechanisms and support clinical translation.
Our team studies how T and B cells interact in human lymphoid structures, with a particular focus on the developing pediatric immune system and chronic inflammation. By exploring these contexts, we aim to better understand how adaptive immune interactions are regulated in human tissues and how they contribute to disease progression and resolution.
About the lab
The lab is part of the Center for Translational Immunology (CTI), which brings together leading immunology expertise to conduct all immunological disease research at University Medical Center Utrecht.
Located in the Wilhelmina Children’s Hospital next to UMC Utrecht and the Princess Maxima Center, the lab benefits from access to diverse clinical samples, enhancing translational research opportunities across diseases and enabling close collaboration with clinicians to improve diagnostics and patient outcomes.
News
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Donation from Rotterdam Fund Racers Supports Research on Targeting TLS in Lung Cancer
During a fundraising event organized by the Rotterdam Fund Racers, money was raised to support cancer research. I am extremely proud and honored to have been selected again as one of the research goals supported by this fundraiser, and to receive €33,000 generated through the generous donations of participants and supporters, all in the spirit…
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Emma and Margot Begin Their Thesis Research Projects
We’re excited to welcome two new thesis students to our research group: Emma and Margot, who have just kicked off their 10-week research projects as part of their Biomedical Sciences training. Over the coming weeks, they’ll dive deep into their own research topics, combining a focused literature review with some hands-on lab training. This structure…
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Science Jam #65 (CCSS): The Complexity Behind Effective Immune Responses
Thanks to the Young Complexity Researchers Utrecht (YCRU) group, they brought these popular sessions back to the CCSS for our researchers to discuss challenges in Complex Systems Studies. Everyone is welcome! Abstract of presentation:The adaptive immune system protects against infection by generating highly specific and long-lasting responses. Germinal centers (GCs) are the sites where high-affinity antibody…
