Lab Updates
Emma and Margot Begin Their Thesis Research Projects
We’re excited to welcome two new thesis students to our research group: Emma and Margot, who have just kicked off their 10-week research projects as part of their Biomedical Sciences training. Over the coming weeks, they’ll dive deep into their own research topics, combining a focused literature review with some hands-on lab training. This structure…
Science Jam #65 (CCSS): The Complexity Behind Effective Immune Responses
Thanks to the Young Complexity Researchers Utrecht (YCRU) group, they brought these popular sessions back to the CCSS for our researchers to discuss challenges in Complex Systems Studies. Everyone is welcome! Abstract of presentation:The adaptive immune system protects against infection by generating highly specific and long-lasting responses. Germinal centers (GCs) are the sites where high-affinity antibody…
ZonMw Open Competition Grant Awarded
The ZonMw Open Competition gives research teams the space to explore new ideas and work together, leading to high-quality, groundbreaking research. It encourages collaboration and allows researchers to study important questions without fixed themes. This project team consists of: Theo van den Broek (UMC Utrecht), Virgil Dalm (Erasmus MC, coordinator), Ines da Silva Serra (Erasmus…
Research Collaboration Published in ‘Journal of Clinical Investigation’
In early life, newborns are exposed to many new antigens, and their immune system must learn to tolerate harmless substances while still defending against threats. This study shows that naïve CD4+ T cells in newborns are especially good at becoming regulatory T cells (Tregs), which help maintain immune tolerance. This enhanced ability is linked to…
Lab Collaboration Results in Publication in ‘Inflammatory Bowel Diseases’
This study explores how autologous hematopoietic stem cell transplantation (aHSCT) reshapes the immune system in people with severe Crohn’s disease who do not respond to conventional treatments. Tracking patients for up to two years, the researchers found strong changes in circulating T cells after transplantation, particularly in those who improved clinically. Interestingly, immune changes in…
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T:B Cell lab 